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Scientific Studies

LifeSign Scientific Studies

Computerized Scheduling of Nicotine Gum Use. January, 1997 by Albert Jerome Ph.D. and Patricia L. Fiero, Ph.D. 8 week study, funded by NCI, testing the feasibility of employing a hand-held computer to implement a scheduled gradual reduction (SGR) protocol for nicotine gum use. Computer technology resolves the difficulties of developing and matching schedules to users associated with the use of gradual fading techniques and avoids the confusion and inconvenience of printed schedules.

Research on the effectiveness of LifeSign for smokeless tobacco cessation was funded through a grant from the NCI. Results showed that 29% of 62 smokeless tobacco users were abstinent four to six weeks after treatment end. Portions of this study were presented at the Society for Research on Nicotine and Tobacco Convention held in San Diego, CA (March, 1995).

"Computer Paced Rate Reductions to Decrease Nicotine and Carbon Monoxide Intake Prior to Cessation of Cigarette Smoking," is based on research done at independent research institutions. Results support the assumption that LifeSign's gradual withdrawal method of smoking cessation produces significant reductions in nicotine levels during use.

"Computer Assisted Smoking Treatment: A Controlled Evaluation and Long-Term Follow-Up" is also published in the Journal of Advancement in Medicine (1992, Volume 5(l), pp. 29-41). This paper is based on research conducted at an independent research institution comparing the relative effectiveness of LifeSign with and without group counseling. Eighteen-month follow-up showed CO validated abstinence rates of 36% among subjects in the group counseling condition and 24% among subjects who used LifeSign without group counseling. Portions of this research were presented at the Annual Convention of the Association for the Advancement of Behavior Therapy held in Washington, DC (November, 1989).

Journal of Advancement in Medicine (1990, Volume 3(2), pp. 131-139). Portions of the research described in this paper were presented at the Annual Scientific Sessions of the Society of Behavioral Medicine held in Washington, DC, in March, 1987, and at the Annual Convention of the Association for the Advancement of Behavior Therapy held in Boston,(November, 1987).

"Development of a Computer-Assisted Smoking Treatment Program: A Preliminary Report," was published by Harvard University's Institute for the Study of Smoking Behavior and Policy in February 1988. This paper presents the results of two clinical trials. The first study reported a one-year carbon monoxide (CO) validated abstinence rate of 18.5%, while the second reported a CO validated one-year abstinence rate of 22%.

DietMate Scientific Studies

Computerized Diet and Exercise Intervention for High Blood Pressure. This paper describes results of a Phase I SBIR study funded by NHLBI examining DietMate as an intervention for High Blood Pressure (Albert Jerome, Ph.D., 1996)

DietMate: A Computerized Intervention for Computer-Assisted Cholesterol Reduction. This paper describes results of a Phase I SBIR study funded by NHLBI examining DietMate as an intervention for cholesterol reduction and weight loss (Albert Jerome, Ph.D., 1992)

DietMate: Computerized Self-Management for Weight Control. This paper provides a conceptual overview and description of the DietMate Program (Albert Jerome, Ph.D. & Lee W. Frederiksen, Ph.D. (1992). Behavior Therapist, 15 (10), 256-258.

DietMate: A Computerized Intervention for Weight Loss. This paper describes the initial DietMate validation study conducted with an early prototype of the product (Albert Jerome, Ph.D., 1991.) This project was funded by a phase I SBIR grant from NIDDK.


 
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